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Prof. Dr. Edward Pearce

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Prof. Dr.
Edward Pearce

Institute of Biology III

Group: Immunometabolism
www.ie-freiburg.mpg.de

Phone: +49 (0)761 5108 476

pearceed@ie-freiburg.mpg.de

 

Focus of research

  • Immunmetabolismus
  • Geweberesidente Immunzellen
  • Immunität gegen Infektionen

CV

  • Since 2015 Senior Group Leader, Max Planck Institute of Immunobiology and Epigenetics
  • Since 2015 Professor, Faculty of Biology, University of Freiburg, Freiburg, Germany
  • 2011-2015 Professor of Pathology & Immunology, Department of Pathology & Immunology, Washington University School of Medicine, St. Louis, MO, USA
  • 2009-2011 Member and Chief Scientific Officer, Trudeau Institute, Saranac Lake, NY, USA
  • 2004-2009 Professor, Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, USA
  • 2001-2003 Associate Professor, Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, USA
  • 1997-2001 Associate Professor, Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, NY, USA
  • 1991-1997 Assistant Professor, Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, NY, USA
  • 1983-1991 Postdoctoral training, Labortory of Parasitic Diseases, NIAID, National Institutes of Health, Bethesda, MD, USA
  • PhD, Division of Parasitology, National Institute for Medical Research, Mill Hill, London, UK (degree awarded by Brunel University).

Selected publications

  • Huang SC, Everts B, Ivanova Y, O'Sullivan D, Nascimento M, Smith AM, Beatty W, Love-Gregory L, Lam WY, O'Neill CM, Yan C, Du H, Abumrad NA, Urban JF Jr, Artyomov MN, Pearce EL, Pearce EJ. 2014. Cell-intrinsic lysosomal lipolysis is essential for alternative activation of macrophages. Nat Immunol. 15(9):846-55 PubMed PMID: 25086775.
  • Everts B, Amiel E, Huang SC, Smith AM, Chang CH, Lam WY, Redmann V, Freitas TC, Blagih J, van der Windt GJ, Artyomov MN, Jones RG, Pearce EL, Pearce EJ. 2014 TLR-driven early glycolytic reprogramming via the kinases TBK1-IKKɛ supports the anabolic demands of dendritic cell activation. Nat Immunol. 15:323-32. PubMed PMID: 24562310.
  • Krawczyk CM, Holowka T, Sun J, Blagih J, Amiel E, DeBerardinis RJ, Cross JR, Jung E, Thompson CB, Jones RG, Pearce EJ. 2010. Toll-like receptor-induced changes in glycolytic metabolism regulate dendritic cell activation. Blood. 115:4742-9. PubMed PMID: 20351312; PubMed Central PMCID: PMC2890190.
  • Glatman Zaretsky A, Taylor JJ, King IL, Marshall FA, Mohrs M, Pearce EJ. 2009. T follicular helper cells differentiate from Th2 cells in response to helminth antigens. J Exp Med. 206:991-9. PubMed PMID: 19380637; PubMed Central PMCID: PMC2715032.
  • Pearce EJ, Caspar P, Grzych JM, Lewis FA, Sher A. 1991. Downregulation of Th1 cytokine production accompanies induction of Th2 responses by a parasitic helminth, Schistosoma mansoni. J Exp Med. 173:159-66. PubMed PMID: 1824635; PubMed Central PMCID: PMC2118762.

 

[Link to complete publication list]

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