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Dr. Robin Teufel

teufel

Dr.
Robin Teufel

Institute of Biology II

Group: Novel Enzymatic Reactions in Bacterial Secondary Metabolism
www.zbsa.uni-freiburg.de

Phone: +49 (0)761 203-97199

robin.teufel@zbsa.uni-freiburg.de

 

Focus of research

  • Microbial natural product biosynthesis, antibiotic resistance & biotechnology
  • Mechanistic and structural investigation of enzymes (e.g., via protein X-ray crystallography)
  • Cofactor biochemistry, particularly of flavin cofactors
  •  

CV

  • 10/2020 Habilitation and Venia Legendi in Microbiology
  • Since 04/2020 DFG-Heisenberg Research Group Leader at the Faculty of Biology, University of Freiburg (Freiburg, Germany).
  • 02/2015-02/2020 DFG-Emmy Noether Nachwuchgruppenleiter an der Fakultät für Biologie und am Zentrum für Biosystemanalyse (ZBSA) der Albert-Ludwigs-Universität Freiburg
  • 2014-2015 NIH-Postdoc am Scripps Institution of Oceanography, Center for Marine Biotechnology & Biomedicine, University of California San Diego (La Jolla, USA) bei Prof. Dr. Bradley S. Moore
  • 2012-2013 DFG-Postdoc am Scripps Institution of Oceanography, Center for Marine Biotechnology & Biomedicine, University of California San Diego (La Jolla, USA) bei Prof. Dr. Bradley S. Moore
  • 2008-2011 Promotion (Dr. rer. nat., summa cum laude) “Aerobic Phenylacetate Catabolism – A novel Principle of Aromatic Degradation” at the University of Freiburg bei Prof. Dr. Georg Fuchs
  • 2001-2008 Diplom in Biologie “Die 3-Hydroxypropionyl-CoA Dehydratase des 3-Hydroxypropionat/4-Hydroxybutyrat-Zyklus der Crenarchaeota“ an der Albert-Ludwigs-Universität Freiburg bei Prof. Dr. Georg Fuchs 

Selected publications

  • Duan Y., Petzold M., Saleem-Batcha R., Teufel R.* Bacterial tropone natural products and derivatives: Overview on the biosynthesis, bioactivities, ecological role and biotechnological potential. ChemBioChem, 21(17), 2384-407 (2020).
  • Matthews A., Saleem-Batcha R., Sanders JN., Stull F., Houk KN., & Teufel R.* Aminoperoxide adducts expand the catalytic repertoire of flavin monooxygenases. Nat. Chem. Biol., 16(5), 556-63 (2020).
  • Tsypik O., Makitrynskyy R., Frensch B., Zechel DL., Paululat T., Teufel R.* (co-corresponding author), Bechthold A.* Oxidative carbon backbone rearrangement in rishirilide biosynthesis. J. Am. Chem. Soc. 142(13), 5913-17 (2020).
  • Saleem-Batcha R., Stull F., Sanders JN., Moore BS., Palfey BA., Houk KN.*, & Teufel R.* Enzymatic control of dioxygen binding and functionalization of the flavin cofactor. Proc. Natl. Acad. Sci. U S A. 115, 4909-14 (2018).
  • Teufel R., Miyanaga A., Michaudel Q., Stull F., Louie G., Noel JP., Baran PS., Palfey B., & Moore BS.* Flavin-mediated dual oxidation controls an enzymatic Favorskii-type rearrangement. Nature 503, 552-6 (2013). 

 

[Link to complete publication list]

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