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Prof. Dr. Wolfgang R. Hess

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Prof. Dr.
Wolfgang R. Hess

Institute of Biology III

Group: Genetics & Experimental Bioinformatics
www.cyanolab.de

Phone: +49 (0)761 203-2796

wolfgang.hess@biologie.uni-freiburg.de

 

Focus of research

  • RNA biology using experimental and biocomputational approaches
  • Microbial systems biology
  • Biology of native CRISPR systems and their application

CV

  • 2017-2019 Senior fellow of the Freiburg Institute for Advanced Studies (FRIAS) and the University of Strasbourg Institute for Advanced Study (USIAS) in France
  • 2012 William Evans Guest Professorship, University of Otago, Dunedin, New Zealand
  • since 2010 Elected Director of the Institute for Biology 3, University of Freiburg, Germany
  • since 2010 Head of the Examination Committee, Faculty of Biology, University of Freiburg, Germany
  • since 2008 Full Professor (W3) for Genetics, Faculty of Biology, University of Freiburg, Germany
  • 2004-2007 Professor for Experimental Bioinformatics (C3), Faculty of Biology, University of Freiburg, Germany
  • 2003-2004 Funding Director, Ocean Genome Legacy Foundation, affiliated with New England Biolabs, Beverly, U.S.
  • 1999-2002 Associate Professor Genetics (C2), Faculty of Natural Sciences, Humboldt-University Berlin, Germany
  • 1999 Habilitation (Genetics), Faculty of Natural Sciences, Humboldt-University Berlin, Germany
  • 1994-1999 Assistant Professor Genetics (C1), Faculty of Natural Sciences, Humboldt-University Berlin, Germany
  • 1993-1994 Postdoctoral Research Fellow, Observatoire Océanologique de Roscoff, CNRS, France
  • 1990 PhD in Genetics (Dr. rer. nat.), Faculty of Natural Sciences, Humboldt-University Berlin, Germany

Selected publications

  • Behler J., Sharma K., Reimann V., Wilde A., Urlaub H., Hess W.R. (2018) The host-encoded RNase E endonuclease as the crRNA maturation enzyme in a CRISPR-Cas subtype III-Bv system. Nature Microbiol. 3, 367–377.
  • Georg J., Kostova G., Vuorijoki L., Schön V., Kadowaki T., Huokko T., Baumgartner D., Müller M., Klähn S., Allahverdiyeva Y., Hihara Y., Futschik M., Aro E.M., Hess W.R. (2017) Acclimation of oxygenic photosynthesis to iron starvation is controlled by the sRNA IsaR1. Current Biology 10, 1425–1436.
  • Reimann V., Alkhnbashi O., Saunders S.J., Scholz I., Hein S., Backofen R., Hess W.R. (2017) Structural constraints and enzymatic promiscuity in the Cas6-dependent generation of crRNAs. Nucleic Acids Research 45, 915-925.
  • Klähn S., Schaal C., Georg J., Baumgartner D., Knippen G., Hagemann M., Muro-Pastor A.M, Hess W.R. (2015) The sRNA NsiR4 is involved in nitrogen assimilation control in cyanobacteria by posttranscriptional regulation of glutamine synthetase inactivation factor IF7. Proc. Natl. Acad. Sci. USA, 112, 6243-6252.
  • Mitschke J., Georg J., Scholz I., Sharma C., Dienst, D., Bantscheff J., Steglich C., Voss B., Wilde, A., Vogel J., Hess W.R. (2011) An experimentally anchored map of transcriptional start sites in the model cyanobacterium Synechocystis sp. PCC 6803. Proc. Natl. Acad. Sci. USA 108, 2124-2129.

 

[Link to complete publication list]

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