apl. Prof. Dr. Gerald Radziwill
apl. Prof. Dr. |
Focus of research
- Molecular mechanisms of signal transduction
- Composition and dynamic of signal complexes
- Optogenetic approaches to control cell fate
CV
- Since 2019 Senior group leader, Faculty of Biology and CIBSS Centre for Integrative Biological Signalling Studies, University of Freiburg, Germany
- Since 2015 Senior group leader, Faculty of Biology and BIOSS Centre for Biological Signalling Studies, University of Freiburg, Germany
- 2009-2015 Deputy Professor for Biochemistry, Faculty of Biology and BIOSS Centre for Biological Signalling Studies, University of Freiburg, Germany
- 2012 Apl. Professor, University of Freiburg
- 2011 Venia legendi for Biochemistry, University of Freiburg, Germany
- 2008 Habilitation/venia legendi for Molecular Medicine, University of Zurich, Switzerland
- 1994-2008 Group leader, Institute of Medical Virology, University of Zurich, Switzerland
- 1989-1993 Postdoctoral researcher, Max Planck Institute of Molecular Genetics, Berlin, Germany
- 1985-1989 PhD, Molecular Biology, ZMBH, University of Heidelberg, Germany
- 1980-1985 Study of Biology, Dipl. Biol., University of Heidelberg, Germany
Selected publications
- Hörner M., Chatelle C., Mühlhäuser W.W.D., Stocker D.R., Coats M., Weber W., Radziwill G. (2018) Optogenetic control of focal adhesion kinase signaling. Cellular Signalling 42, 176–183
- Fischer A., Mühlhäuser W.D., Warscheid B., Radziwill G. (2017) Membrane localization of acetylated CNK1 mediates a positive feedback on RAF/ERK signaling. Science Advances 3, e1700475.
- Mühlhäuser, W.D., Fischer, A., Weber, W., Radziwill, G. (2017) Optogenetics – Bringing light into the darkness of mammalian signal transduction (invited review). BBA Mol Cell Res. 1864, 280-292.
- Fischer, A., Warscheid, B., Weber, W., Radziwill, G. (2016) Optogenetic clustering of CNK1 reveals mechanistic insights in RAF and AKT signaling controlling cell fate decisions. Sci. Rep.6, 38155.
- Wend, S., Wagner, H.J., Müller, K., Zurbriggen, M.D., Weber, W., Radziwill, G. (2014) Optogenetic control of protein kinase activity in mammalian cells. ACS Synth Biol. 3, 280-285.