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Prof. Dr. Bettina Warscheid

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Prof. Dr.
Bettina Warscheid

Institute of Biology II

Group: Functional Proteomics
www.proteomics.uni-freiburg.de

Phone: +49 (0)761 203-2690

bettina.warscheid@biologie.uni-freiburg.de

 

Focus of research

  • The proteome of mitochondria and peroxisomes: biogenesis, dynamics, regulation and function
  • Mitochondrial dysfunctions and communication/signaling
  • Kinase/phosphatase signalling in skeletal muscle cells and B-cells 

CV

  • Since 2018 Vice Dean, Faculty of Biology, University of Freiburg
  • Since 2018 Principle Investigator of the Excellence Cluster CIBSS Centre for Integrative Biological Signalling Studies
  • 2016-2018 Dean, Faculty of Biology, University of Freiburg
  • 2014-2016 Dean of Students, Faculty of Biology, University of Freiburg
  • Since 2010 Full Professor (W3) for Functional Proteomics, Faculty of Biology, University of Freiburg
  • 2009-2010 Professor (W2) for Clinical and Cellular Proteomics, Medical Faculty and Centre for Medical Biotechnology, University of Duisburg-Essen
  • 2004-2009 Junior-Professor (W1) for Protein Mass Spectrometry, University of Bochum
  • 2003-2010 Group Leader Cellular Proteomics, Medical Proteome Center, University of Bochum
  • 2002-2003 Postdoc, University of Maryland, College Park, MD, USA
  • 1997-2002 PhD in Chemistry, Leibniz Institute of Analytical Sciences, Dortmund
  • 1991-1997 Study of Chemistry, Technical University Dortmund

Selected publications

  • Quantitative proteomics identifies redox switches for global translation modulation by mitochondrially produced reactive oxygen species. Topf U, Suppanz I, Samluk L, Wrobel L, Böser A, Sakowska P, Knapp B, Pietrzyk MK, Chacinska A, Warscheid B (2018), Nat Commun 9:324.
  • Definition of a high confidence mitochondrial proteome at quantitative scale. Morgenstern M, Stiller SB, Lübbert P, Peikert CD, Dannenmeier S, Drepper F, Weill U, Höß P, Feuerstein R, Gebert M, Bohnert M, van der Laan M, Schuldiner M, Schütze C, Oeljeklaus S, Pfanner N, Wiedemann N, Warscheid B (2017), Cell Rep 9:2836-2852.
  • Charting organellar importomes by quantitative mass spectrometry. Peikert CD, Mani J, Morgenstern M, Sandro K, Knapp B, Wenger C, Harsman A, Oeljeklaus S, Schneider A, Warscheid B (2017) Nat Commun 8, 15272.
  • Myofibrillar Z-discs are a protein phosphorylation hot spot with protein kinase C (PKCα) modulating protein dynamics. Reimann L, Wiese H, Leber Y, Schwäble AN, Fricke A, Rohland A, Knapp B, Peikert CD, Drepper F, van der Ven PFM, Radziwill G, Fürst DO, Warscheid B (2017) Mol Cell Proteomics 16, 346-367.
  • Mistargeted mitochondrial proteins activate a proteostatic response in the cytosol. Wrobel L, Topf U, Bragoszewski P, Wiese S, Sztolsztener ME, Oeljeklaus S, Varabyova A, Lirski M, Chroscicki P, Mroczek S, Januszewicz E, Dziembowski A, Koblowska M, Warscheid B*, Chacinska A* (2015) Nature 524, 485-488. *corresponding author

 

[Link to complete publication list]

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