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Prof. Dr. Ralf Baumeister


Prof. Dr.
Ralf Baumeister

Institute of Biology III

Group: Bioinformatics and Molecular Genetics

Phone: +49 (0)761 203-8350



Focus of research

  • Genetics and biochemistry of ageing
  • cancer and tumorigenesis
  • Stress response signaling


  • Since 2003 Professor (Ordinarius) of Bioinformatics and Molecular Genetics, University of Freiburg, Germany. Affiliation: Faculties of Biology and of Medicine
  • Since 2013 Furtwangen University, Faculty of Medical and Life Sciences: Member of the Advisory Board
  • 2007-2010 Director of FRIAS LIFENET (Freiburg Institute for Advanced Studies, Section Life Sciences)
  • 2005-2010 Founding Director of ZBSA (Freiburg Center for Systems Biology)
  • 2006-2008 Director of Institute of Biology III
  • 2000-2003 Professor of Metabolic Biochemistry, Faculty of Medicine, LMU University of Munich, Germany
  • 1998 Founder of EleGene Inc., Pharmaceutical and Genetic Screening Company, Martinsried, Germany
  • 1995-2000 Group leader, Genzentrum, LMU University of Munich, Germany
  • 1992-1995 Postdoc, Harvard Medical School, Mass. General Hospital, Boston, USA (lab of Gary Ruvkun)
  • 1988-1992 PhD (Dr. rer nat). in Microbiology and Biochemistry, University of Erlangen (lab of Prof. Wolfgang Hillen) (summa cum laude, excellent)

Selected publications

  • Qi, W., Yan, Y., Pfeifer, D., Donner von Gromoff, E., Wang, Y., Maier, W. and Baumeister R. (2017) DAF-16/FOXO interacts with TGF-ß/BMP signaling to induce germline tumor formation via mTORC1 activation. PLoS Genetics 26;13(5):e1006801
  • Thedieck, K., Holzwarth, B., Prentzell, M.T., Boehlke, C., Kläsener, K., Ruf, S., Sonntag, A.G., Maerz, L., Grellscheid, S., Kremmer, E., Nitschke, R., Kuehn, E.W., Reth, M., Hall, M.N., Baumeister, R. (2013). Inhibition of mTORC1 by Astrin and stress granules prevents apoptosis in cancer cells. Cell. 154(4):859-74.
  • Runkel ED, Liu S, Baumeister R*, Schulze E (2013) Surveillance-Activated Defenses Block the ROS–Induced Mitochondrial Unfolded Protein Response. PLoS Genet 9(3): e1003346. correction: PLoS Genet 2016 12(10):e1006377
  • Fatouros, C., Pir, G.P., Biernat, J., Koushika, S.P., Mandelkow, E., Mandelkow, E., Schmidt, E., Baumeister, R. (2012). Inhibition of Tau aggregation in a novel C. elegans model of Tauopathy mitigates proteotoxicity. Hum Mol Genet. 21(16):3587-603.
  • *Neumann-Haefelin, E., Qi, W., Finkbeiner, E., Walz, G., Baumeister R.* Hertweck, M. (2008). SHC-1/p52Shc targets the insulin/IGF-1 and JNK signaling pathways to modulate life span and stress response in C. elegans. Genes Dev. 22(19):2721-35.* corresponding author.


[Link to complete publication list]

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