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Prof. Dr. Wilfried Weber


Prof. Dr.
Wilfried Weber

Institute of Biology II

Group: Synthetic Biology

Phone: +49 (0)761 203-97654



Focus of research

  • Development and application of optogenetic switches to control signaling processes in mammalian cells
  • Development of interactive and information-processing materials systems
  • Development of biosensors for in vitro analytics


  • Since 2009 Full Professor (W3) of Synthetic Biology
  • 2008-2009 Group Leader, Department of Biosystems Science and Engineering, ETH Zurich, CH
  • 2006-2008 Group Leader, Institute for Chemical and Bioengineering, ETH Zurich, CH
  • 2003-2005 Postdoc, Institute of Biotechnology, ETH Zurich, CH
  • 2000-2003 Doctoral Studies, Research Group Prof. Martin Fussenegger, Institute of Biotechnology, ETH Zurich, CH
  • 2000 Diploma in Biotechnology, Ecole Supérieure de Biotechnologie de Strasbourg, Strasbourg, F

Selected publications

  • Phytochrome-based extracellular matrix with reversibly tunable mechanical properties. Hörner M, Raute K, Hummel B, Madl J, Creusen G, Thomas OS, Christen EH, Hotz N, Gübeli RJ, Engesser R, Rebmann B, Lauer J, Rolauffs B, Timmer J, Schamel WWA, Pruszak J, Römer W, Zurbriggen MD, Friedrich C, Walther A, Minguet S, Sawarkar R, Weber W. Adv Mater. 2019; DOI: 10.1002/adma.201806727
  • Optogenetic control of integrin–matrix interaction. Baaske J, Mühlhäuser WWD, Yousefi OS, Zanner S, Radziwill G, Hörner M, Schamel WWA, Weber W (2019). Communications Biology. DOI: 10.1038/s42003-018-0264-7
  • Synthetic biology-inspired design of signal-amplifying materials systems. Wagner HJ, Engesser R, Ermes K, Geraths C, Timmer J, Weber W. Materials Today 2018; doi: 10.1016/j.mattod.2018.04.006
  • Synthetic Biology makes polymer materials count. Beyer HM, Engesser R, Hörner M, Koschmieder J, Beyer P, Timmer J, Zurbriggen MD, Weber W. Adv Mater. 2018 May;30(21):e1800472
  • Multianalyte antibiotic detection on an electrochemical microfluidic platform. Kling A, Chatelle C, Armbrecht L, Qelibari E, Kieninger J, Dincer C, Weber W, Urban G. Anal Chem. 2016 Oct 18;88(20):10036-10043.


[Link to complete publication list]

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